Restylane® and Perlane® are safe and natural cosmetic dermal fillers that restore volume and fullness to the skin to correct facial wrinkles and folds, such as nasolabial folds.*
Restylane and Perlane are made of hyaluronic acid, a natural substance that already exists in the human body. The hyaluronic acid in Restylane is a crystal-clear gel called NASHA™ or Non-Animal Stabilized Hyaluronic Acid. NASHA is completely biocompatible with human hyaluronic acid.
Restylane maintains its shape using the body's own moisture. The hyaluronic acid in Restylane is hydrophilic or "water loving." As hyaluronic acid gradually degrades, each molecule binds to more water and over time, the same volume can be maintained with less hyaluronic acid. This ability of hyaluronic acid to bind to water is what helps provide the duration of results.
Perlane has larger gel particles and is intended to be injected deeper within the skin.
Unlike rooster-derived hyaluronic acids and bovine collagen products, Restylane is free from animal proteins. This limits any risk of animal-based disease transmissions or development of allergic reactions to animal proteins.
After your treatment, you might have some redness or swelling. This will normally last less than seven days. Sunbathing and cold outdoor activities should be avoided until any redness or swelling disappears.*
Frequently asked questions*
Where can Restylane be used?
Restylane® has been used in more than 3 million treatments in over 70 countries to correct a variety of wrinkles and to enhance the appearance of the lip border. It is currently approved in the U.S. for the treatment of facial wrinkles and folds, such as nasolabial folds, which are the lines from the nose to the corners of the mouth.
How long does Restylane last?
Studies have shown that Restylane effects generally last for about six months. The unique NASHA™ technology helps maintain the cosmetic effect until the injected material is nearly gone. Follow-up treatments are typically scheduled at six-month intervals. (Individual results may vary.)
What are pre-treatment precautions?
Before being treated with Restylane® or Perlane® you should take a few precautions. Prior to treatment, avoid using aspirin, nonsteroidal anti-inflammatory medications, St. John’s wort, or high doses of vitamin E supplements. These agents may increase bruising and bleeding at the injection site. Also, if you have previously suffered from facial cold sores, discuss this with your doctor, who may prescribe a medication to minimize recurrence.
Is Restylane safe?
Since 1996, over 3 million Restylane® treatments have been safely administered by dermatologists and plastic surgeons in more than 70 countries. This innovative treatment is now approved in the U.S. for the treatment of facial wrinkles and folds.
Restylane has a highly favorable safety profile. It's composed of Non-Animal Stabilized hyaluronic acid. Hyaluronic acid is a substance found naturally in the human body. Restylane is fully biocompatible. There is limited risk of animal-based disease transmission or development of allergic reactions to animal proteins. No allergy testing is required before use.
Based on clinical studies, Restylane treatments produce a low occurrence of adverse events. The most commonly reported side effects were temporary redness and swelling at the injection site. These effects typically resolve in less than seven days.
How much does Restylane cost?
Restylane® is injected in a customized procedure based on your specific needs, so the cost will vary from patient to patient. In general, the cost of Restylane treatment is comparable to the cost of similar procedures. In our office the price may range from $500 and up depending on area of injection and amount of medication used. However, Restylane's properties often prove to be very economical over the long term.
What are the advantages of Restylane?
Restylane® is different from Botox®.
Restylane is natural, cosmetic filler. Botox is a drug that blocks nerve transmission and relaxes the underlying muscles. Many patients have been very pleased after receiving treatment with both products.
Restylane is different than other hyaluronic acid-based products and bovine collagen. Unlike rooster-derived hyaluronic acids and bovine collagen products, Restylane is free from animal proteins. This limits any risk of animal-based disease transmissions or development of allergic reactions to animal proteins. Bovine collagen is derived from cowhide and requires an allergy test. Restylane can be administered without pretesting, so no waiting is required.
What are my Restylane post-treatment instructions?
Cold compresses (a cloth dipped in cold water, wrung out, and applied to the injected area) may be used immediately after treatment to reduce swelling.
Avoid touching the treated area during the 6 hours following treatment, so you do not accidentally injure your skin while the area is numb. After that, the area can be gently washed with soap and water.
Until any redness or swelling goes away, avoid exposure of the treated area to intense heat (sun lamp or sunbathing).
If you have previously suffered from facial cold sores, there is a risk that the needle punctures could contribute to another recurrence.
Avoid taking aspirin, nonsteroidal anti-inflammatory medications, St. John’s wort, or high doses of vitamin E supplements for one week after treatment. These agents may increase bruising and bleeding at the injection site.
Please be sure to consult your healthcare professional if you experience side effects beyond 14 days. Also, ask your healthcare professional about recommendations for a follow-up appointment.
Recently approved by the FDA, Juvederm™ injectable gel is a “next-generation” dermal filler. The smooth consistency gel helps to instantly restore your skin's volume and smooth away facial wrinkles and folds, like your "smile lines" (nasolabial folds—the creases that run from the bottom of your nose to the corners of your mouth).
Juvederm™ dermal filler is the only dermal filler currently available with the highest concentration of hyaluronic acid and a special formulation process. This process creates a smooth gel that flows easily into the skin, creating smooth, natural looks.*
All other currently approved hyaluronic acid dermal fillers use a gel particle suspension formulation. These gel particles may be visibly seen as opposed to the smoother formulation used in Juvederm™. The smooth consistency of Juvederm™ dermal filler also may help to minimize the discomfort that can sometimes occur during the injection procedure. In addition, Juvederm™ injectable gel is the first FDA-approved hyaluronic acid dermal filler that is proven to be safe and effective for persons of color.*
Before and After FAQ
Belotero Balance Dermal Filler is an FDA approved injectible filler that quickly integrates into the skin. Belotero Balance is FDA-approved for injection into the mid-to-deep dermis for correction of moderate-to-severe facial wrinkles and folds, such as nasolabial folds. Once injected, it instantly smooths the lines and wrinkles in your face. While Belotero Balance is made of the same material (hyaluronic acid) as some of the other fillers, Belotero Balance has unique properties that allow it adapt within the skin for soft results. The filler may last about 6 months or more according to the manufacturer - Merz Aesthetics. As with other fillers, there is very little to no down-time associated with a Belotero Balance procedure.*
* Results may vary